I think he'll come back.
There's some fights for him for sure, but it's gonna take more than a couple of Lesnar fights to dig the UFC out of this financial slump they're in. I'm not saying he should be expected to single-handedly return the UFC to it's Golden Age, just that we shouldn't expect it, either.
With that said, I'd like to see him fight JDS, Roy Nelson, and Bigfoot Silva, in no particular order.